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Bromelain and quercetin have a synergistic effect on each other

And honestly, for most people, that probably means taking reasonable doses, timing them well, making sure you have adequate folate and other supporting nutrients, and checking in with your healthcare provider periodically to make sure everythings on track.

Nat Rev Dis Primers

Li, H., Sun, L., Gao, P

The different blots include two fractions of the supernatant of the OE lysate (extract S1 for lane 1 and extract S2 for lane 2, all panels), the pellet of the OE lysate (extract C for lane 3, all panels), the nasal mucus (lane 4) and the purified recombinant rat GSTM2 (100 ng) (lane 5, panel A and B) or the purified recombinant human GSTA1 (100 ng) (lane 5, panel A)

A comprehensive methylfolate supplement can go a long way in supporting proper liver detoxification and the methylation processes involved in repairing DNA, turning genes on and off, estrogen clearance, and getting around the MTHFR gene mutation